منابع مشابه
Collagen-mimetic peptide-modifiable hydrogels for articular cartilage regeneration
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Collagens are over-expressed in various human cancers and subsequently degraded and denatured by proteolytic enzymes, thus making them a target for diagnostics and therapeutics. Genetically engineered bacteriophage (phage) is a promising candidate for the development of imaging or therapeutic materials for cancer collagen targeting due to its promising structural features. We genetically engine...
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Self-assembling peptides have been previously designed that assemble into macroscopic membranes, nanotapes, and filaments through electrostatic interactions. However, the formation of highly ordered collagen-like fibrils, which display D-periodic features, has yet to be achieved. In this report, we describe for the first time a synthetic peptide system that self-assembles into a fibrous structu...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2020
ISSN: 1525-7797,1526-4602
DOI: 10.1021/acs.biomac.0c00103